CorNeat eShunt

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Glaucoma impacts 80 million patients globally. Glaucoma is a disease that damages the eye's optic nerve. It usually happens when aqueous humor builds up in the front of the eye (Anterior Chamber). This extra fluid increases the eye's intraocular pressure, damaging the optic nerve. Damage to the optic nerve caused by glaucoma leads to loss of visual field, usually starting from the periphery and eventually leading to the loss of central vision and blindness. 

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Current solutions, aimed at controlling the intraocular pressure by reducing the aqueous humor production or increasing its drainage/absorption, include drops, laser surgery, MIGS (Minimally Invasive Glaucoma Shunts), incisional (angle) surgery and glaucoma drainage devices (shunt). None of which provide a long-term remedy. 

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The CorNeat eShunt is determined to revolutionize the treatment of glaucoma. It is designed to regulate the intraocular pressure and addresses the shortcomings of existing solutions. Using advanced materials, the eShunt inlet, which is placed in the anterior chamber angle, mimics the trabecular mesh function in terms of flow resistance. The eShunt outlet is uniquely positioned in the intraconal space, an area that does not scar and clog and can absorb the drained aqueous humor. The eShunt tube, which is covered by a synthetic ECM layer, seamlessly integrates with the ocular tissue as it traverses the subconjunctival space. 

Features

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• Inlet (regulating pressure)

  • Provides deterministic IOP - inlet mimics trabecular meshwork's adaptive pressure regulation as flow increases with pressure elevation.

• Outlet (location)

  • Prolonged patency - outlet uniquely positioned deep in the orbit where there is only fat and no scar tissue.

• Tube (ocular Integration)

  • Biologically integrates with neighboring tissue - porous, biocompatible, non-degradable polymers mimicking human Extra Cellular Matrix (ECM).